Continuous MODIS/Terra satellite thermal infrared remote sensing data of the Jinggu MS6.6 earthquake area from July 2014 to January 2015 is collected, and after cloud-removing, the thermal infrared data between 5:00a.m.-7:00a.m. Beijing Time, which is the best period for observation, is selected to perform land surface temperature data retrieval and analyze the temporal evolution of land surface temperature anomalies before and after the earthquake, as well as the relationship between abnormal spatial distribution and active fault. The impacts of non-structural factors such as topography, landform and seasonal weather of the earthquake zone on land surface temperature anomalies are discussed. The result shows that: a)there was thermal infrared anomalous temperature increase appearing near the epicenter two months before the MS6.6 Jinggu earthquake and there was a certain correspondence between the anomalous temperature increase and earthquake occurrence time. The significant temperature increase happened in the first half of the month, reached its peak 7 days before the earthquake, and dropped rapidly after the earthquake. At the same time, there was also anomalous temperature increase to a certain extent appearing about half month before the strong aftershocks of magnitude 5.8 and 5.9; b)Through the correlation analysis of non-structural factors such as topography, landform and seasonal weather of the earthquake zone, it is found that the structural "temperature increase" before the Jinggu MS6.6 earthquake was the information indicating the anti-season change of temperature increase in the earthquake zone; c)The anomalous temperature increase was cross-developed from the epicenter along the NS-NE trending conjugate faults, which is consistent roughly with the NNE-SSW predominant direction of the maximum principal stress of the regional tectonic stress field. After full consideration of the influence of non-structural factors such as topography, landform and seasonal weather on the abnormal temperature increase, it is inferred that this thermal infrared temperature increase is possibly a short-imminent anomaly before the earthquake.