The MS6.4 earthquake occurred in Yangbi County, Dali Prefecture, Yunnan Province on May 21, 2021, the epicenter is located at the southwest boundary of Sichuan-Yunnan rhomboid block, where Weixi-Qiaohou-Weishan Fault meets Honghe Fault. According to data released by the China Earthquake Networks Center, the Yangbi MS6.4 earthquake is the only earthquake in recent years with MS>6.0 in the epicentral region. The National Strong-Motion Observation Network System(NSMONS)of China has built strong motion stations with relatively large density in Yunnan and Sichuan Provinces, NSMONS has obtained a large number of high quality strong ground motion acceleration recordings during this earthquake. In the process of earthquake, the different characteristics of strong ground motion often lead to the different characteristics of building structure damage in the epicentral region. In-depth analysis of ground motion observation characteristics is helpful to deepen the understanding of earthquake damage.In this study, the NGA-West 2 data processing flow and reasonable and reliable high-pass filtering frequency selection criteria were used to process 29 sets of strong ground motion acceleration recordings of the earthquake, we obtained reliable peak ground acceleration(PGA), peak ground velocity(PGV), and 5%damped acceleration response spectra(SA). We drew the spatial distribution maps of PGA and PGV in the E-W, N-S, and U-D directions, compared the observed ground motion PGA, SA with the calculated values of the ground motion attenuation relationships commonly used in western China and Sichuan-Tibet region, and analyzed the amplitude and time-frequency characteristics of the observed ground motions, and a comparative analysis was performed between the spectral acceleration recorded by the near-field stations with the design spectra of the code for seismic design of buildings in China. Combined with the on-site earthquake damage investigation, the main reasons for the lighter structural damage in the meizoseismal area were analyzed.The results show that the maximum horizontal PGA and PGV of the Yangbi MS6.4 earthquake recorded by the station both locate near the epicenter and the horizontal ground motion attenuates the slowest along the north-northwestern direction, which is basically the same as the long axis direction of isoseismals of seismic intensity map released by Yunnan Earthquake Agency. However, the vertical ground motion attenuates the slowest along the near north-south direction. The actual observation values on the soil site in the Yangbi earthquake are in good agreement with the calculated values of the horizontal ground motion attenuation relationships commonly used in western China and Sichuan-Tibet region, while the observation values on the bedrock site are smaller than the calculated values of the horizontal ground motion attenuation relationships commonly used in western China and Sichuan-Tibet region, which indicates the horizontal ground motion attenuation relationships commonly used in western China and Sichuan-Tibet region derived from the transfer method may over-predict the observation values on the bedrock site. According to the time-frequency diagram obtained by using the wavelet transform, the energy recorded in the EW and NS directions of the station 53YBX, which is the nearest station to the epicenter, is mainly concentrated in 8~15Hz, and the corresponding period range is 0.07~0.13s, while the energy recorded in the UD direction is mainly concentrated in 20Hz, and the corresponding period range is about 0.05s. When the period is smaller than 0.14s, the spectral accelerations in the EW and NS directions of the station 53YBX is significantly higher than the basic ground motion design spectra and rare ground motion design spectra of the code for seismic design of buildings in China; the remarkable period of the acceleration response spectra is 0.1s, the reaction spectrum decreases rapidly when the period is greater than 0.1s, the spectral acceleration corresponding to the superior period in the N-S direction of station 53YBX is 3.87 times the value of the rare ground motion design spectra platform. Most buildings near the epicenter are the one-story old timber frame structures which were built in the 1980s and 1990s, with a natural period of 0.1s, and the 2~3-story brick and concrete frame structures which were built in recent years. According to the analysis of above ground motion characteristics of the Yangbi MS6.4 earthquake, the most serious damage of this earthquake is the one-story old timber frame structure, while the 2~3-story brick and concrete frame structure has little damage or very light damage. This phenomenon should be related to the characteristics of the structure itself and the disrepair of the structure, the extremely rich ground motion component with a period of 0.1s, and the relatively less ground motion component with a period of more than 0.14s.